Ozempic or Mounjaro Face? Here's how to fix it.

In recent years, medications like Ozempic and Mounjaro have surged in popularity for their effectiveness in weight loss and diabetes management. These treatments, however, have led many users to report a change in their facial appearance, commonly referred to as "Ozempic face" or "Mounjaro face." This condition describes changes such as sagging skin, hollow cheeks, and a tired look that may arise due to rapid fat loss. If you are experiencing these changes, rest assured you are not alone. In this post, we will dive into the causes behind these facial alterations and explore effective solutions.

Understanding Ozempic and Mounjaro Face

The term "Ozempic face" highlights the changes some individuals notice while using GLP-1 receptor agonists, like Ozempic and Mounjaro. These medications are designed to promote weight loss by reducing appetite and increasing feelings of fullness. While they can be life-changing for those wanting to lose weight, quick weight loss can lead to sagging skin and a hollow appearance.

Statistics show that approximately 50% of users experience some form of negative facial change due to rapid weight loss. When you lose weight too quickly, your skin may not have enough time to adjust, resulting in what many describe as a sunken or empty face, or a tired appearance. Recognising these changes is the first step toward addressing them effectively.

Causes of Sagging Skin and Hollow Face

A youthful face is supported by lots of plump fat pads that provide structure, support and shape to our faces. As we age, these fat pads shrink and separate, and a decline in collagen and elastin causes the skin appearance to change and lose its strength and elasticity. We also get shrinkage of the bone around the eyes, cheeks and jawline in a process known as bone resorption. This loss of scaffolding that holds the skin taught essentially deflates leading to sagging skin and loss of those youthful, plump facial features as the years go by. However, if you are overweight, these changes will be hidden by the extra fat under your skin.

When weight loss happens quickly, especially through GLP-1 medications, the skin doesn’t always have time to adapt. This results in a face that may look slimmer, but also more tired or aged than before causing issues such as:

• Flatter, less defined cheeks

• Hollowness under the eyes

• Sagging skin around the jawline or neck creating jowls or so called ‘turkey neck’

• More visible fine lines and skin folds

  
  

Can You Prevent “Ozempic Face”?

While you can’t completely control how your body loses fat, you can support your skin health throughout your weight loss journey. You should always follow the individual diet and exercise advice given to you by your provider.

Here’s some other ways you can improve your skin health during your weight loss journey:

• Prioritise skin nutrition: Take a daily high strength hydrolysed collagen supplement with vitamin C and omega-3 fats to support the skin’s structure from within.

• Maintain a high protein diet: To reduce muscle loss from the face and body.

• Stay hydrated: Adequate hydration maintains skin plumpness and elasticity.

• Maintain a steady pace of weight loss: Slow and consistent loss gives your skin time to adapt.

• Invest in medical-grade skincare: Formulations with peptides, retinoids, and hyaluronic acid improve resilience and firmness.

  
  

Even with these steps, some level of facial volume loss is natural and cannot be prevented. This is where aesthetic treatments may help.

How to Treat Facial Sagging After Weight Loss

At Skin Redefined in Cheltenham, we often see clients who’ve achieved amazing body transformations through medical weight loss or lifestyle change, but feel their face no longer reflects how vibrant they feel inside. Our approach focuses on restoring balance, lift, and luminosity using evidence-based, non-surgical techniques.

1. Restore Structure with Dermal Fillers

Loss of volume in the cheeks, under the eyes, and jawline is one of the most noticeable changes after weight loss injections such as Mounjaro, Wegovy or Ozempic.

Hyaluronic acid dermal fillers can be used strategically to:

• Rebuild contour and definition

• Smooth hollow areas

• Support sagging skin along the jawline to help improve the signs of jowsl

• Recreate natural lift without looking “done”.

  
  

We focus on subtle, balanced enhancement, giving you back the structure your skin has lost, without making you look overdone and importantly- still looking like you, just a more refreshed version.

2. Tighten and Smooth with Radiofrequency Microneedling

For skin that’s feeling looser or thinner after weight loss, RF microneedling is one of the most effective solutions.

By combining gentle microneedling with controlled heat energy, it stimulates new collagen and elastin, tightening and rejuvenating the skin over time. It’s particularly effective for:

• Softening lines around the mouth

• Lifting the lower face and jaw

• Firming the neck

  
  

At Skin Redefined, we use advanced technology which achieves deep rejuvenation with minimal downtime- ideal for restoring firmness after rapid fat loss.

3. Enhance Radiance with Skin Boosters and Polynucleotides

When you lose weight quickly, the skin can sometimes look dull or dehydrated. Skin boosters like Profhilo, Sunekos or Polynucleotides restore hydration, plump the skin, reduce sagging and improve texture. They work by stimulating natural collagen production, giving your skin that supple, healthy glow that’s often lost during the weight loss process.

Why Choose a Medically-Led Clinic

At Skin Redefined, treatments are carried out by an Advanced Aesthetics Nurse Prescriber, ensuring every plan is safe, medically informed, and completely tailored to your needs. We focus on natural outcomes that make you look refreshed- never overfilled or altered. Our patients often say they feel “like themselves again” after treatment, just healthier, more lifted, and more radiant.

What to do next

If you’ve experienced facial changes after weight loss injections such as Ozempic or Mounjaro, remember that these effects are both normal and treatable. With the right skin support and advanced non-surgical treatments, it’s entirely possible to restore structure, lift sagging skin, and bring back your natural glow, all while continuing your health journey with confidence. If you're curious about which treatments may be appropriate for you, we suggest booking a consultation with our Nurse Prescriber, Kelly Whittaker at our discreetly located Cheltenham clinic.

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